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Submitted: 19 Dec 2020
Accepted: 26 Dec 2020
ePublished: 30 Dec 2020
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Disease and Diagnosis. 2020;9(4): 158-162.
doi: 10.34172/ddj.2020.06
  Abstract View: 5
  PDF Download: 10

Original Article

Comparing the Effects of Aloe Vera Ointment with Routine Treatment on the Severity of Diaper Dermatitis: A Randomized Controlled Double-Blinded Clinical Trial

Shiva Heidari 1 ORCID logo, Naser Parizad 2 ORCID logo, Fatemeh Shirazi 3 ORCID logo, Vahid Alinejad 4, Sima Ghanipour Badelbuu 2* ORCID logo

1 Nursing and Midwifery School, Urmia Islamic Azad University, Urmia, Iran.
2 Patient Safety Research Center, Clinical Research Institute, Nursing & Midwifery School, Urmia University of Medical Sciences, Urmia, Iran.
3 Nursing and Midwifery School, Shiraz University of Medical Sciences, Shiraz, Iran.
4 Medical School, Urmia University of Medical Sciences, Urmia, Iran.
*Correspondence to Sima Ghanipour Badelbuu, Patient Safety Research Center, Clinical Research Institute, Nursing & Midwifery School, Urmia University of Medical Sciences, Urmia, Iran. Tel: +98443275 4961; Email: ghanipourfrnzvsf@ gmail.com

Abstract

Background: Diaper dermatitis (DD) is a prevalent skin disease in children, which causes child discomfort and parental concern. This study aimed to compare the effects of aloe vera ointment with routine treatment on the severity of DD in hospitalized children.

Materials and Methods: This double-blinded randomized clinical trial was carried out on 60 children aged less than two years admitted to Tabriz pediatric hospital in Iran from February to June 2017. Using convenience sampling method, the patients were assigned into two equal groups (n=30 in each) of intervention and control. The intervention group received routine combination treatment, whereas the control group received aloe vera ointment. The patients were examined on the first, third, and sixth days of the study. Data analysis was performed using SPSS software (version 22) and descriptive and analytical statistics.

Results: The severity of DD in both groups improved on the sixth day compared to the first day. In comparison, no significant difference was observed between the two groups regarding the severity of dermatitis (P>0.05).

Conclusion: Herbal products cause fewer side effects than chemical products and seem to have significant pharmacological effects on the skin. Thus, aloe vera ointment appears to help treat DD and, with further studies, may emerge as a possible therapeutic option.

Keywords: Diaper rash, Aloe vera, Ointments, Randomized controlled trial, Iran
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