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Submitted: 09 Jan 2022
Revision: 07 Feb 2022
Accepted: 08 Feb 2022
ePublished: 01 Apr 2023
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Dis Diagn. 2023;12(2): 101-105.
doi: 10.34172/ddj.2023.392
  Abstract View: 333
  PDF Download: 160

Case Report

Adrenal Incidentaloma With the Diagnosis of Normotensive Pheochromocytoma: A Case Report

Ali AtashAbParvar 1 ORCID logo, Feysal Yousefzade 2 ORCID logo, Somayeh Kheirandish 1 ORCID logo, Sepehr Rasekhi 2 ORCID logo, Ghazal Zoghi 3 ORCID logo, Masoumeh Kheirandish 1* ORCID logo

1 Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
2 Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
3 Cardiovascular Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
*Corresponding Author: Masoumeh Kheirandish, Email: kheirandishm@yahoo.com

Abstract

Background: Pheochromocytomas (PCCs) are catecholamine-producing neuroendocrine tumors that originate from the adrenal medulla. Their clinical presentations most commonly include hypertension, headache, palpitations, and sweating; however, PCCs are sometimes normotensive and clinically silent.

Case Presentation: A female patient with abdominal pain as well as persistent and crushing left flank pain for the past six months was examined. The imaging studies revealed a mass in the upper pole of the left kidney indicative of a potential adrenal gland tumor; however, she had normal blood pressure (BP). Histopathologic examination of the mass from exploratory laparotomy showed that it was a PCC. Findings from sonography and computed tomography (CT) scan of the left adrenal tumor, along with elevated urinary normetanephrine level and positive iodine-123 metaiodobenzylguanidine (MIBG) scan led to preoperative diagnosis of PCC in our case.

Conclusion: This study highlighted the importance of imaging and biochemical testing in diagnosing PCCs in patients with adrenal incidentalomas (AIs), even though they were normotensive and entirely asymptomatic.

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