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Submitted: 05 Oct 2022
Revision: 01 Nov 2022
Accepted: 06 Nov 2022
ePublished: 13 Dec 2022
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Dis Diagn. 2023;12(1): 35-41.
doi: 10.34172/ddj.2023.455
  Abstract View: 203
  PDF Download: 174

Original Article

Investigating Laboratory Biochemical Factors in Different Types of Patients With Cardiovascular Diseases

Zeinab Bandani Tarashoki 1 ORCID logo, Naser Kamyari 2 ORCID logo, Atefeh Zahedi 3 ORCID logo, Alireza Hazbenejad 1 ORCID logo, Maryam Ban 4 ORCID logo, Khadijeh Kanani 5 ORCID logo, Esmat Radmanesh 6,7* ORCID logo

1 Student Research Committee of Abadan University of Medical Sciences, Abadan, Iran.
2 Department of Public Health, School of Health, Abadan University of Medical Sciences, Abadan, Iran.
3 Asadabad School of Medical Sciences, Asadabad, Iran.
4 School of Nursing, Abadan University of Medical Sciences, Abadan, Iran.
5 Clinical Research Development Unit of Taleghani Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran.
6 Department of Physiology, Abadan University of Medical Sciences, Abadan, Iran.
7 Clinical Research Development Unit of Valiasr Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran.
*Corresponding Author: Correspondence to Esmat Radmanesh, Emails: esmatradmanesh33@ gmail.com, , Email: e.radmanesh@abadanums.ac.ir

Abstract

Background: Due to the destructive effect of cardiovascular disease on vital organs, the study of laboratory biochemical factors in the most common heart diseases is essential to accelerate the treatment of cardiovascular patients.

Materials and Methods: This study was cross-sectional and analytical. By referring to the hospital information system of educational hospitals of the Abadan University of Medical Sciences, the necessary information of 565 patients with cardiovascular diseases (e.g., demographic information and laboratory diagnostic markers) from March 21, 2019, to March 19, 2020, was extracted through the hospital information system and completed checklist. Data analysis was performed using SPSS software version 22.

Results: In this study, fasting blood sugar (FBS), international normalized ratio (INR), erythrocyte sedimentation rate (ESR), Serum glutamate pyruvate transaminase (SGPT), serum glutamate oxalate transaminase (SGOT), creatinine, blood urea nitrogen (BUN), total bilirubin, creatine kinase (CK)- MB, and prothrombin time (PT) were higher than normal in patients with cardiovascular diseases. SGOT was significantly different between age groups (P=0.006), and the highest value was observed in the age group over 75 years. Moreover, FBS was significantly different between the male and female groups (P=0.002).

Conclusion: FBS and some diagnostic markers such as renal markers, liver, coagulation, and inflammatory markers are abnormal in patients with cardiovascular diseases.

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